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Hi,
Thank you for posting your query on Microsoft Community.
I would like to inform you that if the programs are not compatible then you can run the game in compatible mode in Windows 10.
To run the game in Windows Compatibility mode.
Uninstall and Install the Game in compatibility mode:
a) Download the Game
b) Right-click on the Game setup file and click on ‘properties’.
c) Click on the ‘compatibility’ tab and check the box ‘Run this program in compatibility mode for’ and select Windows 7 operating system from the drop down.
d) Click on ‘Apply’ and click ‘OK’ and run the file to install it.
Make older programs compatible with this version of Windows
Most programs created for earlier versions of Windows also work in this version of Windows, but some older programs might run poorly or not at all. If a program written for an earlier version of Windows doesn't work correctly, you can try changing the compatibility settings for the program, either by using the Program Compatibility Troubleshooter or manually choosing compatibility settings.
Also refer to the below link:
Can I uninstall Windows 10 if I do not like it or something goes wrong?
Civ 3 Conquests Windows 10 Download
See the following: How to: Rollback to a previous version of Windows from Windows 10
Civ3 Conquests Windows 10
Hope this information helps and let us know the status of the issue we will be glad to help you further.